Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.55 |
| ▸ | ABCC9 | O60706 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216547 | 1.00 | CYP3A4 (0.58) | CYP3A4ALOX15ABCB1ABCC9KDM4E | |
| SCHEMBL9216538 | 1.00 | CYP3A4 (0.58) | CYP3A4ALOX15ABCB1ABCC9KDM4E | |
| SCHEMBL9214370 | 0.90 | CYP3A4 (0.54) | CYP3A4ALOX15ABCB1ABCC9 | |
| SCHEMBL9214362 | 0.90 | CYP3A4 (0.54) | CYP3A4ALOX15ABCB1ABCC9 | |
| SCHEMBL9214355 | 0.90 | CYP3A4 (0.54) | CYP3A4ALOX15ABCB1ABCC9 | |
| SCHEMBL9221492 | 0.82 | ABCC9 (0.65) | CYP3A4ALOX15ABCB1ABCC9KDM4E | |
| SCHEMBL9221479 | 0.82 | ABCC9 (0.65) | CYP3A4ALOX15ABCB1ABCC9KDM4E | |
| SCHEMBL9221502 | 0.82 | ABCC9 (0.65) | CYP3A4ALOX15ABCB1ABCC9KDM4E | |
| SCHEMBL9211353 | 0.81 | ABCB1 (0.60) | ABCB1ABCC9KDM4E | |
| SCHEMBL9211358 | 0.81 | ABCB1 (0.60) | ABCB1ABCC9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375449-B1 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1995-02-15 | — | — | EP | claimed |
| EP-0375449-A2 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | claimed |
| EP-0375449-B1 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1995-02-15 | — | — | EP | disclosed |
| EP-0375449-A2 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |