SCHEMBL9216610

SCHEMBL9216610

COC(=O)c1cc2cccc(OC)c2cc1OC

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.74
ALDH1A1 P00352 6/20 0.74
HPGD P15428 5/20 0.74
HSD17B10 Q99714 4/20 0.74
NPSR1 Q6W5P4 1/20 0.55
POLB P06746 1/20 0.49
GAA P10253 4/20 0.46
MAPT P10636 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
IRAK4 Q9NWZ3 3/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5344077 0.88 KDM4E (0.61) KDM4EALDH1A1HPGDHSD17B10NPSR1
SCHEMBL17137307 0.88 KDM4E (0.57) KDM4EALDH1A1HPGDHSD17B10NPSR1
SCHEMBL400926 0.85 KDM4E (0.77) KDM4EALDH1A1HPGDHSD17B10POLB
SCHEMBL551105 0.85 ALDH1A1 (1.00) KDM4EALDH1A1HPGDHSD17B10POLB
SCHEMBL29353299 0.85 ALDH1A1 (1.00) KDM4EALDH1A1HPGDHSD17B10POLB
SCHEMBL19338219 0.84 HSD17B10 (0.70) KDM4EALDH1A1HPGDHSD17B10POLB
SCHEMBL8203011 0.84 ALDH1A1 (0.58) KDM4EALDH1A1HPGDHSD17B10NPSR1
SCHEMBL8202357 0.84 KDM4E (0.58) KDM4EALDH1A1HPGDHSD17B10NPSR1
SCHEMBL29352187 0.84 KDM4E (0.74) KDM4EALDH1A1HPGDHSD17B10POLB
SCHEMBL30660792 0.84 ALDH1A1 (0.74) KDM4EALDH1A1HPGDHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0492178-B1 Naphthoic acid derivative FUJIREBIO KK (JP) 1995-10-04 EP disclosed
US-5324728-A Lipoxygenase inhibiting antiallergens FUJIREBIO INC. (JP) 1994-06-28 US disclosed
EP-0492178-A2 Naphthoic acid derivative FUJIREBIO INC. (JP) 1992-07-01 EP disclosed