Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217214 | 0.90 | NPSR1 (0.45) | NPSR1LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9214398 | 0.88 | NPSR1 (0.41) | NPSR1LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9217007 | 0.81 | LMNA (0.36) | NPSR1LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9209425 | 0.80 | LMNA (0.48) | NPSR1LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9213951 | 0.80 | NPSR1 (0.45) | NPSR1LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9216348 | 0.80 | LMNA (0.36) | NPSR1LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9545491 | 0.78 | LMNA (0.35) | NPSR1LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9544901 | 0.77 | LMNA (0.34) | NPSR1LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9216480 | 0.77 | POLB (0.46) | NPSR1LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9219938 | 0.75 | LMNA (0.38) | NPSR1LMNACYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644879-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-03-29 | — | — | EP | claimed |
| WO-1993025535-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1993-12-23 | — | — | WO | claimed |
| EP-0644879-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025535-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1993-12-23 | — | — | WO | disclosed |