Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23686215 | 0.91 | HTT (0.53) | HPGDNPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL9217138 | 0.89 | HTT (0.51) | HPGDNPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL23686213 | 0.89 | HTT (0.51) | HPGDNPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL23686118 | 0.88 | KDM4E (0.64) | HPGDNPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL23686109 | 0.87 | HTT (0.49) | HPGDNPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL23686191 | 0.86 | ABCC1 (0.67) | HPGDSMN1; SMN2KDM4ECACNA1FCACNA1D | |
| SCHEMBL9220053 | 0.86 | HTT (0.48) | HPGDNPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL9119964 | 0.86 | HTT (0.48) | HPGDNPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL23686450 | 0.85 | MEN1 (0.61) | HPGDNPSR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL9222512 | 0.85 | HTT (0.47) | HPGDNPSR1SMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525568-B1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1995-05-10 | — | — | EP | claimed |
| US-5328931-A | Nervous sytem disorders, cognition activators | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | claimed |
| US-5328931-A | Nervous sytem disorders, cognition activators | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |