Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704130 | 0.79 | — | — | |
| SCHEMBL1219183 | 0.79 | — | — | |
| SCHEMBL1809605 | 0.75 | TSHR (0.61) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL3065185 | 0.72 | TSHR (0.58) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL3065183 | 0.72 | TSHR (0.58) | TSHRGABRR1GABRR2BLMGABRR3 | |
| Ammonia Solution, Strong SCHEMBL38659341 | 0.72 | TSHR (0.58) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL15848598 | 0.72 | TSHR (0.46) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL7911535 | 0.71 | PPARA (0.41) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL3504406 | 0.71 | PPARA (0.59) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL3504409 | 0.71 | PPARA (0.59) | TSHRGABRR1GABRR2BLMGABRR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449099-B1 | Retinoide derivatives, their preparation and their use for medicaments | HOFFMANN LA ROCHE (CH) | 1995-11-29 | — | — | EP | claimed |