Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216519 | 0.79 | ALDH1A1 (0.56) | PDK1CYP2C9ALDH1A1KDM4EPOLB | |
| SCHEMBL9213501 | 0.77 | KDM4E (0.50) | PDK1CYP2C9ALDH1A1PPOXKDM4E | |
| SCHEMBL9215570 | 0.77 | ALDH1A1 (0.54) | PDK1CYP2C9ALDH1A1KDM4EAHR | |
| SCHEMBL16264455 | 0.77 | CYP2C9 (0.58) | PDK1CYP2C9ALDH1A1KDM4EAHR | |
| SCHEMBL9218853 | 0.75 | ALDH1A1 (0.55) | PDK1CYP2C9ALDH1A1KDM4EPOLB | |
| SCHEMBL9217591 | 0.75 | CYP2C9 (0.48) | PDK1CYP2C9PPARAALDH1A1KDM4E | |
| SCHEMBL9208158 | 0.75 | CYP2C9 (0.45) | CYP2C9ALDH1A1KDM4EAHRPOLB | |
| SCHEMBL9208442 | 0.75 | ALDH1A1 (0.48) | PDK1CYP2C9ALDH1A1KDM4EAHR | |
| SCHEMBL9208444 | 0.75 | ALDH1A1 (0.48) | PDK1CYP2C9ALDH1A1KDM4EAHR | |
| SCHEMBL9217714 | 0.73 | ALDH1A1 (0.55) | PDK1ALDH1A1PPOXKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |