Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217837 | 1.00 | ALDH1A1 (0.66) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9217260 | 0.96 | ALDH1A1 (0.66) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9217256 | 0.96 | ALDH1A1 (0.66) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9209926 | 0.95 | ALDH1A1 (0.58) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9209928 | 0.95 | ALDH1A1 (0.58) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9209260 | 0.90 | ALDH1A1 (0.61) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9209265 | 0.90 | ALDH1A1 (0.61) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9217069 | 0.86 | ALDH1A1 (0.67) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9217073 | 0.86 | ALDH1A1 (0.67) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9214213 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HTTPKMMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475214-B1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LTD (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5326785-A | Arteriosclerosis andn diseases of the circulatory system | SUNTORY LIMITED (JP) | 1994-07-05 | — | — | US | disclosed |
| US-5232941-A | Therapeutic agents for diseases of the circulatory system | SUNTORY LIMITED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0475214-A1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |