Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197534 | 0.94 | AKR1B1 (0.60) | AKR1B1ALDH1A1MAPTRAB9A | |
| SCHEMBL10998677 | 0.91 | AKR1B1 (0.58) | AKR1B1ALDH1A1MAPTRAB9A | |
| SCHEMBL11615502 | 0.90 | AKR1B1 (0.57) | AKR1B1ALDH1A1MAPTRAB9A | |
| SCHEMBL11611821 | 0.90 | AKR1B1 (0.57) | AKR1B1ALDH1A1MAPTRAB9A | |
| Isoxepac SCHEMBL24970 | 0.87 | AKR1B1 (0.81) | AKR1B1ALDH1A1MAPTRAB9A | |
| Isoxepac SCHEMBL29588437 | 0.87 | AKR1B1 (0.81) | AKR1B1ALDH1A1MAPTRAB9A | |
| SCHEMBL13696688 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MAPTRAB9A | |
| SCHEMBL10373496 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAPTRAB9A | |
| SCHEMBL677820 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPT | |
| SCHEMBL9218391 | 0.83 | ALDH1A1 (0.60) | AKR1B1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082850-A | TOPICAL APPLICATION OF A 6,11-DIHYDROBENZ(B,E)OXEPIN-ALKANOIC ACID OR DERIVATIVES THEREOF | AMERICAN HOECHST CORPORATION (US) | 1978-04-04 | — | — | US | claimed |
| EP-0419844-B1 | N-hydroxy-dibenz[b,e]oxepin-alkylamines and -alkanoic acid amides, related heterocyclic analogues, a process for their preparation and their use in the manufacture of medicaments | HOECHST ROUSSEL PHARMA (US) | 1995-04-05 | — | — | EP | disclosed |
| US-5116863-A | Antiallergens, antiinflammatory agents; asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0419844-A1 | N-hydroxy-dibenz[b,e]oxepin-alkylamines and -alkanoic acid amides, related heterocyclic analogues, a process for their preparation and their use in the manufacture of medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4751238-A | ANALGESICS, ANTIINFLAMMATORY AGENT | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-06-14 | — | — | US | disclosed |
| US-4526891-A | Analgesics | HOECHST ROUSSEL PHARMACEUTICALS INC. (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0119540-A2 | Substituted alkylamine derivatives of 6,11-dihydro-11-oxodibenz (b,e)-oxepins, a process for the preparation and intermediates thereof and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4082850-A | TOPICAL APPLICATION OF A 6,11-DIHYDROBENZ(B,E)OXEPIN-ALKANOIC ACID OR DERIVATIVES THEREOF | AMERICAN HOECHST CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |