Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.59 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218067 | 1.00 | ALDH1A1 (0.73) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9219607 | 0.89 | ALDH1A1 (0.58) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9219597 | 0.89 | ALDH1A1 (0.58) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9209926 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9209928 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9216633 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9219843 | 0.86 | ALDH1A1 (0.65) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9219834 | 0.86 | ALDH1A1 (0.65) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9219829 | 0.86 | ALDH1A1 (0.65) | ALDH1A1HTTPKMMAPTKMT2A | |
| SCHEMBL9215603 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HTTPKMMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475214-B1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LTD (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5326785-A | Arteriosclerosis andn diseases of the circulatory system | SUNTORY LIMITED (JP) | 1994-07-05 | — | — | US | disclosed |
| US-5232941-A | Therapeutic agents for diseases of the circulatory system | SUNTORY LIMITED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0475214-A1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |