Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 7/20 | 0.40 |
| ▸ | FNTB | P49356 | 7/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574986 | 0.82 | FNTA (0.58) | PARP1HCRTR1HCRTR2FNTAFNTB | |
| SCHEMBL8453359 | 0.82 | FNTA (0.59) | PARP1FNTAFNTBPOLB | |
| SCHEMBL8574983 | 0.82 | FNTA (0.58) | PARP1HCRTR1HCRTR2FNTAFNTB | |
| SCHEMBL8453364 | 0.82 | FNTA (0.59) | PARP1FNTAFNTBPOLB | |
| SCHEMBL8573446 | 0.78 | PARP1 (0.52) | PARP1HCRTR1HCRTR2FNTAFNTB | |
| SCHEMBL8573445 | 0.78 | PARP1 (0.52) | PARP1HCRTR1HCRTR2FNTAFNTB | |
| SCHEMBL7628124 | 0.76 | FNTA (0.70) | PARP1MGLLHCRTR1HCRTR2FNTA | |
| SCHEMBL8574801 | 0.73 | FNTA (0.51) | PARP1FNTAFNTBMEN1KMT2A | |
| SCHEMBL5740252 | 0.73 | FNTA (0.51) | PARP1FNTAFNTBPOLB | |
| SCHEMBL5740245 | 0.73 | FNTA (0.51) | PARP1FNTAFNTBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000497-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1995-01-05 | — | — | WO | disclosed |