Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209788 | 0.92 | NPC1 (0.47) | SMN1; SMN2LMNARAB9ANPC1L3MBTL1 | |
| SCHEMBL9278098 | 0.89 | NPC1 (0.35) | SMN1; SMN2LMNARAB9ANPC1L3MBTL1 | |
| SCHEMBL9209794 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNARAB9ANPC1L3MBTL1 | |
| SCHEMBL9211087 | 0.81 | NPC1 (0.35) | SMN1; SMN2LMNARAB9ANPC1L3MBTL1 | |
| SCHEMBL9213079 | 0.80 | FFAR1 (0.37) | SMN1; SMN2KDM4EMAPTFFAR1TBXAS1 | |
| SCHEMBL9218845 | 0.80 | PPARG (0.43) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL9216433 | 0.79 | MTNR1A (0.33) | FFAR1TBXAS1 | |
| SCHEMBL9275150 | 0.79 | MEN1 (0.37) | L3MBTL1FFAR1TBXAS1 | |
| SCHEMBL9211094 | 0.76 | NPC1 (0.36) | SMN1; SMN2LMNARAB9ANPC1L3MBTL1 | |
| SCHEMBL9032937 | 0.76 | NPC1 (0.43) | SMN1; SMN2LMNARAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |