Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216027 | 0.94 | L3MBTL1 (0.57) | L3MBTL1RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL9212926 | 0.94 | L3MBTL1 (0.57) | L3MBTL1RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL9218007 | 0.94 | L3MBTL1 (0.68) | L3MBTL1RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL9219278 | 0.92 | L3MBTL1 (0.57) | L3MBTL1RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL9431339 | 0.84 | POLB (0.66) | L3MBTL1ALDH1A1HSD17B10KDM4ETSHR | |
| SCHEMBL9217396 | 0.83 | TP53 (0.71) | L3MBTL1ALDH1A1HSD17B10KDM4ETSHR | |
| SCHEMBL9218548 | 0.81 | TDP1 (0.57) | L3MBTL1RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL9431067 | 0.80 | RXFP1 (0.62) | ALDH1A1HSD17B10KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL9430103 | 0.79 | TP53 (0.51) | L3MBTL1RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL9430659 | 0.79 | POLB (0.60) | ALDH1A1HSD17B10KDM4ETSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994026738-A1 | N'-HETEROCYCLYL-N-BENZOFURANYL UREA DERIVATIVES AND THEIR ANALOGS AS ACAT INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |