Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MDH1 | P40925 | 11/20 | 0.58 |
| ▸ | MDH2 | P40926 | 11/20 | 0.58 |
| ▸ | SHBG | P04278 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23268748 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP3A4MDH1MDH2SHBG | |
| SCHEMBL6699973 | 0.85 | SMN1; SMN2 (0.70) | SMN1; SMN2CYP3A4MDH1MDH2SHBG | |
| SCHEMBL8042635 | 0.85 | NPC1 (0.51) | SMN1; SMN2 | |
| SCHEMBL9219214 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP3A4MDH1MDH2SHBG | |
| SCHEMBL9220908 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP3A4MDH1MDH2SHBG | |
| SCHEMBL6153892 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2CYP3A4MEN1KMT2AHIF1A | |
| Formaldehyde SCHEMBL28598675 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP3A4MDH1MDH2SHBG | |
| SCHEMBL1836425 | 0.80 | CYP3A4 (0.54) | SMN1; SMN2CYP3A4MDH1MDH2SHBG | |
| SCHEMBL28598670 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4MDH1MDH2SHBG | |
| SCHEMBL9787240 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP3A4MDH1MDH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5429918-A | Antifading agent | FUJI PHOTO FILM CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |