Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042635 | 0.84 | NPC1 (0.51) | SMN1; SMN2MAOBRAB9APOLBNPC1 | |
| SCHEMBL10506137 | 0.84 | MEN1 (0.58) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL1283871 | 0.83 | SMN1; SMN2 (1.00) | SMN1; SMN2MEN1KMT2ARAB9ANR4A2 | |
| SCHEMBL8219820 | 0.83 | SMN1; SMN2 (0.73) | SMN1; SMN2MAOBAOC3MEN1KMT2A | |
| SCHEMBL9219224 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1KMT2ACYP3A4HIF1A | |
| SCHEMBL6153890 | 0.81 | SMN1; SMN2 (0.71) | SMN1; SMN2MAOBAOC3MEN1KMT2A | |
| SCHEMBL733369 | 0.81 | SMN1; SMN2 (0.71) | SMN1; SMN2MAOBAOC3MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28429402 | 0.81 | SMN1; SMN2 (0.96) | SMN1; SMN2MEN1KMT2ARAB9ANR4A2 | |
| SCHEMBL12622683 | 0.81 | SMN1; SMN2 (0.71) | SMN1; SMN2MAOBAOC3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4640626 | 0.81 | SMN1; SMN2 (0.96) | SMN1; SMN2MEN1KMT2ARAB9ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382909-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2023-11-30 | — | — | US | disclosed |
| US-20230374008-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2023-11-23 | — | — | US | disclosed |
| WO-2023114451-A1 | UPR MODULATORS TO TREAT HEARING LOSS | JACARANDA BIOSCIENCES, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | L'OREAL (FR) | 2007-04-26 | — | — | US | disclosed |
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
| US-5294530-A | amine developers emulsion layer containing a yellow or cyan coupler and a phenolic derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| US-5104782-A | Silver halide color photographic material containing a pyrazoloazole based coupler and having excellent color reproduction characteristics and which provides images having excellent light fastness | FUJI PHOTO FILM CO., LTD. (JP) | 1992-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | HPGD, KRT18, PTGS1 | SMN1; SMN2 4573/4885MAOB 842/4885AOC3 811/4885 |
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | SMN1; SMN2 2211/4885MAOB 3660/4885AOC3 2700/4885 |
| US-20230382909-A1 | BICYCLIC COMPOUNDS | SLC10A1, PKD1, CYP11B2 | SMN1; SMN2 611/4885MAOB 1212/4885AOC3 2860/4885 |
| US-20230374008-A1 | BICYCLIC COMPOUNDS | SLC10A1, PKD1, CYP11B2 | SMN1; SMN2 611/4885MAOB 1212/4885AOC3 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.