Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.48 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219304 | 1.00 | MAPT (0.64) | MAPTSMN1; SMN2POLBPKMMMP1 | |
| Hydrochloric Acid SCHEMBL7269708 | 0.99 | MAPT (0.62) | MAPTSMN1; SMN2POLBPKMMMP1 | |
| SCHEMBL7268138 | 0.89 | KMT2A (0.56) | MAPTSMN1; SMN2POLBPKMLDHA | |
| SCHEMBL7268142 | 0.89 | KMT2A (0.56) | MAPTSMN1; SMN2POLBPKMLDHA | |
| SCHEMBL7269161 | 0.86 | FKBP1A (0.62) | MAPTSMN1; SMN2POLBPKMLDHA | |
| SCHEMBL7269160 | 0.86 | FKBP1A (0.62) | MAPTSMN1; SMN2POLBPKMLDHA | |
| SCHEMBL9832234 | 0.86 | FKBP1A (0.62) | MAPTSMN1; SMN2POLBPKMLDHA | |
| SCHEMBL7278526 | 0.85 | HSD17B10 (0.59) | CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL7349517 | 0.85 | HSD17B10 (0.59) | CACNA2D1CACNA1BCACNB1CACNA1C | |
| Hydrochloric Acid SCHEMBL7278911 | 0.84 | MAPT (0.54) | MAPTSMN1; SMN2POLBPKMMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378689-A | Hypotensive agents; administrable by mouth | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |