Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6220874 | 0.93 | KCNH2 (0.43) | FDPSPOLBKCNH2HDAC3HDAC4 | |
| SCHEMBL8916827 | 0.91 | KCNH2 (0.42) | FDPSPOLBKCNH2HDAC3HDAC4 | |
| SCHEMBL8915431 | 0.91 | KCNH2 (0.42) | FDPSPOLBKCNH2HDAC3HDAC4 | |
| SCHEMBL8916904 | 0.91 | KCNH2 (0.42) | FDPSPOLBKCNH2HDAC3HDAC4 | |
| SCHEMBL8915171 | 0.91 | KCNH2 (0.42) | FDPSPOLBKCNH2HDAC3HDAC4 | |
| SCHEMBL9083173 | 0.91 | FDPS (0.43) | FDPSPOLBKCNH2HDAC3HDAC4 | |
| SCHEMBL9082073 | 0.90 | FDPS (0.40) | FDPSPOLBKCNH2HDAC3HDAC4 | |
| SCHEMBL9082704 | 0.89 | KCNH2 (0.44) | FDPSPOLBKCNH2MTNR1AMTNR1B | |
| SCHEMBL7165932 | 0.87 | FDPS (0.52) | FDPSHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8914859 | 0.85 | FDPS (0.50) | FDPSPOLBHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464509-B1 | Biphosphonic acid derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-30 | — | — | EP | disclosed |