Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18258500 | 0.84 | GPR3 (0.54) | GPR3KDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL36332 | 0.77 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL4696033 | 0.77 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL9160474 | 0.77 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL29374932 | 0.77 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL10476774 | 0.77 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL30515127 | 0.77 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1TDP1 | |
| Hydrogen Sulfide SCHEMBL23748456 | 0.75 | GPR3 (0.65) | GPR3KDM4EMAPTALDH1A1TDP1 | |
| Ammonia Solution, Strong SCHEMBL6303550 | 0.75 | GPR3 (0.65) | GPR3KDM4EMAPTALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL585838 | 0.75 | GPR3 (0.65) | GPR3KDM4EMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643713-A1 | PYRROLO(1,2-B)-(1,2)-BENZOTHIAZIN-10-ONE AND ITS USE AS AN ANTIMICROBIAL | THE DOW CHEMICAL COMPANY (US) | 1995-03-22 | — | — | EP | disclosed |
| WO-1994022876-A1 | PYRROLO(1,2-B)-(1,2)-BENZOTHIAZIN-10-ONE AND ITS USE AS AN ANTIMICROBIAL | THE DOW CHEMICAL COMPANY (US) | 1994-10-13 | — | — | WO | disclosed |
| US-5270307-A | Pyrrolo(1,2-b)-(1,2)-benzothiazin-10-one and its use as an antimicrobial | THE DOW CHEMICAL COMPANY (US) | 1993-12-14 | — | — | US | disclosed |