Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756390 | 0.80 | NPC1 (0.57) | SMN1; SMN2NPC1RAB9ATDP1GAA | |
| SCHEMBL706559 | 0.75 | MEN1 (0.63) | CES2CES1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7157005 | 0.73 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL3421840 | 0.72 | KDM4E (0.53) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL29493451 | 0.72 | KDM4E (0.53) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL3418472 | 0.71 | RXFP1 (0.57) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL696231 | 0.71 | NPC1 (0.56) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL3421532 | 0.71 | RXFP1 (0.43) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL759767 | 0.71 | CCNA2 (0.58) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL15637834 | 0.71 | LMNA (0.54) | SMN1; SMN2GAALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644879-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-03-29 | — | — | EP | disclosed |