Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080115 | 0.96 | FTO (0.54) | FTOPABPC1MEN1KMT2AKDM4E | |
| SCHEMBL9210190 | 0.95 | FTO (0.47) | FTOPABPC1MEN1KMT2AKDM4E | |
| SCHEMBL9218691 | 0.93 | FTO (0.48) | FTOPABPC1MEN1KMT2AKDM4E | |
| SCHEMBL9217035 | 0.91 | FTO (0.49) | FTOPABPC1MEN1KMT2AKDM4E | |
| SCHEMBL9079262 | 0.91 | FTO (0.51) | FTOPABPC1MEN1KMT2AKDM4E | |
| SCHEMBL9080576 | 0.90 | FTO (0.46) | FTOPABPC1MEN1KMT2AKDM4E | |
| SCHEMBL9080275 | 0.90 | FTO (0.46) | FTOPABPC1MEN1KMT2AKDM4E | |
| SCHEMBL9079817 | 0.88 | FTO (0.47) | FTOPABPC1MEN1KMT2AKDM4E | |
| SCHEMBL9220267 | 0.86 | FTO (0.52) | FTOPABPC1MEN1KMT2AKDM4E | |
| SCHEMBL9078910 | 0.86 | FTO (0.54) | FTOPABPC1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000490-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-05 | — | — | WO | claimed |