Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29897293 | 0.91 | MAPT (0.61) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL985801 | 0.91 | MAPT (0.61) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2086989 | 0.91 | MAPT (0.61) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3538406 | 0.87 | HSD17B10 (0.53) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11643839 | 0.85 | TDP1 (0.59) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9655337 | 0.85 | MAPT (0.53) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL30907664 | 0.84 | MAPT (0.65) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4038925 | 0.84 | MAPT (0.65) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5099839 | 0.84 | MAPT (0.65) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL824063 | 0.84 | MAPT (0.52) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439828-A | Fluorgenic and chomogenic three-dimensional ionophores as selective reagents for detecting ions in biological fluids | ALLIEDSIGNAL INC. (US) | 1995-08-08 | — | — | US | disclosed |
| EP-0371992-B1 | IONOPHORES AS REAGENTS FOR DETECTING IONS | ALLIED SIGNAL INC (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5162525-A | FLUOROGENIC AND CHROMOGENIC THREE-DIMENSIONAL IONOPHORES AS SELECTIVE REAGENTS FOR DETECTING IONS IN BIOLOGICAL FLUIDS | ALLIED-SIGNAL INC. (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0371992-A1 | IONOPHORES AS REAGENTS FOR DETECTING IONS. | ALLIED SIGNAL INC (US) | 1990-06-13 | — | — | EP | disclosed |
| WO-1989000997-A1 | IONOPHORES AS REAGENTS FOR DETECTING IONS | ALLIED-SIGNAL INC. (US) | 1989-02-09 | — | — | WO | disclosed |