Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220403 | 0.85 | MAPT (0.52) | MAPTALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL27630962 | 0.84 | CYP19A1 (0.55) | MAPTALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL11820701 | 0.84 | ALDH1A1 (0.51) | MAPTALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL16943506 | 0.84 | ALDH1A1 (0.53) | MAPTALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL16063141 | 0.84 | ALDH1A1 (0.51) | MAPTALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL13788938 | 0.83 | MAPT (0.56) | MAPTALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL89210 | 0.83 | MAPT (0.55) | MAPTALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL985801 | 0.83 | MAPT (0.61) | MAPTALDH1A1TDP1CYP3A4CYP19A1 | |
| SCHEMBL29897293 | 0.83 | MAPT (0.61) | MAPTALDH1A1TDP1CYP3A4CYP19A1 | |
| SCHEMBL2086989 | 0.83 | MAPT (0.61) | MAPTALDH1A1TDP1CYP3A4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355492-B1 | REACTIVE DYES | BAYER AG (DE) | 1992-12-09 | — | — | EP | disclosed |
| US-5138054-A | Colorfastness, photostability; red dye | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |