Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.34 |
| ▸ | AQP1 | P29972 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209494 | 0.80 | MALT1 (0.38) | MALT1SLC6A4ADRA2AADRA2BADRA2C | |
| SCHEMBL9215221 | 0.80 | MALT1 (0.36) | MALT1SLC6A4ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9273659 | 0.78 | HTR2A (0.37) | MALT1SLC6A4ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9278206 | 0.77 | MALT1 (0.35) | MALT1SLC6A4ADRA2AADRA2BADRA2C | |
| SCHEMBL9210918 | 0.75 | MALT1 (0.43) | MALT1HTR2BHTR2C | |
| SCHEMBL9869729 | 0.74 | MALT1 (0.38) | MALT1 | |
| Hydrochloric Acid SCHEMBL9274817 | 0.73 | DRD2 (0.38) | SLC6A4ADRA2CHTR2BHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9275494 | 0.72 | KDM4E (0.38) | SLC6A4ADRA2CHTR2BHTR2AHTR2C | |
| SCHEMBL9220092 | 0.71 | DRD2 (0.46) | SLC6A4HTR2BHTR2AHTR2CSLC6A3 | |
| SCHEMBL9210567 | 0.70 | HTR2A (0.40) | HTR2BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389425-B1 | Benzotiopyranyl amines | CIBA GEIGY AG (CH) | 1995-04-26 | — | — | EP | disclosed |
| US-5071858-A | Antipsychotic benzothiopyranylamines | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0389425-A1 | Benzotiopyranyl amines | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |