SCHEMBL9220630

SCHEMBL9220630

CC=[Zr](Cc1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.38
HTR2A P28223 2/20 0.35
HTR6 P50406 1/20 0.35
KDM4E B2RXH2 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29479999 0.79 SIGMAR1 (0.39) SIGMAR1HTR2AHTR6KDM4ELMNA
SCHEMBL6055286 0.79 SIGMAR1 (0.39) SIGMAR1HTR2AHTR6KDM4ELMNA
SCHEMBL5273072 0.79 SIGMAR1 (0.39) SIGMAR1HTR2AHTR6KDM4ELMNA
SCHEMBL7187087 0.78 RET (0.32) HTR2AHTR6
SCHEMBL28747647 0.76 SIGMAR1 (0.38) SIGMAR1HTR2AHTR6
SCHEMBL8161340 0.75 RET (0.33) HTR6
Hydrochloric Acid SCHEMBL9202544 0.75 SIGMAR1 (0.37) SIGMAR1HTR2AHTR6KDM4EMEN1
Hydrochloric Acid SCHEMBL4478389 0.75 SIGMAR1 (0.37) SIGMAR1HTR2AHTR6KDM4EMEN1
Hydrochloric Acid SCHEMBL27531769 0.75 SIGMAR1 (0.38) SIGMAR1HTR2AHTR6KDM4EMEN1
SCHEMBL9220624 0.74 SIGMAR1 (0.36) SIGMAR1HTR2AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0283164-B1 Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers MITSUI PETROCHEMICAL IND (JP) 1995-05-24 EP disclosed
EP-0406912-A2 Process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-01-09 EP disclosed
EP-0285443-A1 Process for producing solid catalyst for polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-05 EP disclosed
EP-0283164-A2 Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-21 EP disclosed