Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.68 |
| ▸ | PPARG | P37231 | 7/20 | 0.68 |
| ▸ | PPARD | Q03181 | 7/20 | 0.68 |
| ▸ | PPARA | Q07869 | 7/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | TLR2 | O60603 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | FABP4 | P15090 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.68 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valeric Acid SCHEMBL29134031 | 0.92 | AKR1B1 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL28677917 | 0.90 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Undecanoate SCHEMBL28945595 | 0.90 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Oleic Acid SCHEMBL10973597 | 0.90 | PPARG (0.74) | PPARGPPARDPPARATSHRPTPN1 | |
| Oleic Acid SCHEMBL29829618 | 0.90 | PPARG (0.74) | PPARGPPARDPPARATSHRPTPN1 | |
| Stearic Acid SCHEMBL7720492 | 0.90 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL21145131 | 0.90 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL21145275 | 0.90 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL21145159 | 0.90 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL21145075 | 0.90 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057779-C | N-sulfamino-polymer, fibre formed from it, and their magnetic recording medium | SANYO CHEMICAL IND LTD (JP) | 2000-10-25 | — | — | CN | disclosed |
| CN-1133304-A | N-sulfamino-polymer, fibre formed from it, and their magnetic recording medium | SANYO CHEMICAL IND LTD (JP) | 1996-10-16 | — | — | CN | disclosed |
| US-5401571-A | Magnetic recording media having a binder comprising a sulfobetaine containing polyurethane resin | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0343576-B1 | Binders for magnetic recording media and magnetic recording media | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-4898922-A | Urethane resins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0343576-A2 | Binders for magnetic recording media and magnetic recording media | Takeda Chemical Industries, Ltd. (JP) | 1989-11-29 | — | — | EP | disclosed |
| EP-0146897-B1 | MAGNETIC RECORDING MEDIUM | SONY CORPORATION (JP) | 1989-08-30 | — | — | EP | disclosed |
| EP-0143337-B1 | MAGNETIC RECORDING MEDIUM | SONY CORPORATION (JP) | 1989-07-19 | — | — | EP | disclosed |
| EP-0311935-A2 | Urethane resins | Takeda Chemical Industries, Ltd. (JP) | 1989-04-19 | — | — | EP | disclosed |
| US-4801392-A | FREE RADICAL POLYMERIZATION OR CROSSLINKING | THE MEAD CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |
| US-4731292-A | Magnetic recording medium | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-03-15 | — | — | US | disclosed |
| US-4637959-A | MULTILAYER, MAGNETIC LAYER ON SUBSTRATE POLYUREAURETHANE COPOLYMER | SONY CORPORATION (JP) | 1987-01-20 | — | — | US | disclosed |
| US-4634633-A | THERMOPLASTIC POLYURETHANE-UREA | SONY CORPORATION (JP) | 1987-01-06 | — | — | US | disclosed |
| US-4632878-A | ELECTRON BEAM CROSSLINKED POLYESTER URETHANE POLY(METH)ACRYLATE CONTAINING ISOCYANURATE RINGS | FUJI PHOTO FILM CO., LTD. (JP) | 1986-12-30 | — | — | US | disclosed |
| EP-0146897-A2 | Magnetic recording medium | SONY CORPORATION (JP) | 1985-07-03 | — | — | EP | disclosed |
| EP-0143337-A1 | Magnetic recording medium | SONY CORPORATION (JP) | 1985-06-05 | — | — | EP | disclosed |
| US-4337288-A | WITH CONTROLLED SURFACE ROUGHNESS | FUJI PHOTO FILM CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| US-4253886-A | Corrosion resistant ferromagnetic metal powders and method of preparing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |