Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.48 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 3/20 | 0.40 |
| ▸ | PYGM | P11217 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15284881 | 0.81 | PYGB (0.49) | PYGBOGAPYGLPYGMTSHR | |
| SCHEMBL29406981 | 0.81 | PYGB (0.49) | PYGBOGAPYGLPYGMTSHR | |
| SCHEMBL28379664 | 0.81 | PYGB (0.49) | PYGBOGAPYGLPYGMTSHR | |
| SCHEMBL1674154 | 0.81 | PYGB (0.49) | PYGBOGAPYGLPYGMTSHR | |
| SCHEMBL29484208 | 0.81 | PYGB (0.49) | PYGBOGAPYGLPYGMTSHR | |
| SCHEMBL10357870 | 0.80 | PYGB (0.51) | PYGBOGAPYGLPYGMTSHR | |
| SCHEMBL30569120 | 0.72 | PYGB (0.43) | PYGBOGAPYGLPYGMTSHR | |
| SCHEMBL31598843 | 0.72 | PYGB (0.43) | PYGBOGAPYGLPYGMTSHR | |
| SCHEMBL20677443 | 0.71 | PYGB (0.37) | PYGBPYGLPYGMTSHR | |
| SCHEMBL9448378 | 0.71 | PYGB (0.44) | PYGBOGAPYGLPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003809-A2 | USE OF GLUCOKINASE INHIBITORS FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATING TUMOURS | ISIS INNOVATION LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |