SCHEMBL922148

SCHEMBL922148

O=CC[PH2]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5772312 0.62
SCHEMBL3512374 0.60
SCHEMBL9617505 0.60
SCHEMBL640102 0.58
Malonaldehyde SCHEMBL7515120 0.58
Propionaldehyde SCHEMBL620551 0.55
Hydrochloric Acid SCHEMBL9110824 0.55
Fluoride SCHEMBL9108389 0.55
SCHEMBL10399881 0.51
Malonaldehyde SCHEMBL10949336 0.51 ALDH1A1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2138502-B1 PROCESS FOR PRODUCING PHOSPHORUS-CONTAINING DEHYDROAMINO ACID MEIJI SEIKA PHARMA CO LTD (JP) 2014-02-19 EP disclosed
US-8481779-B2 Method for producing N-substituted-2-amino-4-(hydroxymethylphosphinyl)-2-butenoic acid MEIJI SEIKA PHARMA CO., LTD. (JP) 2013-07-09 US disclosed
US-20120316358-A1 METHOD FOR PRODUCING N-SUBSTITUTED-2-AMINO-4-(HYDROXYMETHYLPHOSPHINYL)-2-BUTENOIC ACID MEIJI SEIKA PHARMA CO., LTD. (JP) 2012-12-13 US disclosed
US-8329935-B2 Process for producing phosphorus-containing dehydroamino acid MEJI SEIKA KAISHA LTD. (JP) 2012-12-11 US disclosed
EP-2522673-A1 METHOD FOR PRODUCING N-SUBSTITUTED-2-AMINO-4-(HYDROXYMETHYLPHOSPHINYL)-2-BUTENOIC ACID Meiji Seika Pharma Co., Ltd. (JP) 2012-11-14 EP disclosed
US-20110009662-A1 PROCESS FOR PRODUCING PHOSPHORUS-CONTAINING DEHYDROAMINO ACID MEIJI SEIKA KAISHA LTD. (JP) 2011-01-13 US disclosed
EP-2138502-A1 PROCESS FOR PRODUCING PHOSPHORUS-CONTAINING DEHYDROAMINO ACID Meiji Seika Kaisha Ltd. (JP) 2009-12-30 EP disclosed