SCHEMBL92225

SCHEMBL92225

CS(=O)(=O)Nc1ccc(OCCO)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.69
RAB9A P51151 2/20 0.69
HPGD P15428 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
AR P10275 1/20 0.58
KCNH2 Q12809 2/20 0.57
CACNA1F O60840 1/20 0.57
CHRM2 P08172 1/20 0.57
ACHE P22303 1/20 0.57
AGTR1 P30556 1/20 0.57
DRD3 P35462 1/20 0.57
CACNA1D Q01668 1/20 0.57
CACNA1S Q13698 1/20 0.57
CACNA1C Q13936 1/20 0.57
LMNA P02545 3/20 0.56
MAPK1 P28482 2/20 0.56
LTA4H P09960 1/20 0.56
PGR P06401 1/20 0.53
KIF11 P52732 2/20 0.51
GRIN1 Q05586 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14113144 0.84 NPC1 (0.93) NPC1RAB9AHPGDSMN1; SMN2AR
SCHEMBL9123987 0.83 NPC1 (0.69) NPC1RAB9AHPGDSMN1; SMN2AR
SCHEMBL5145130 0.83 NPC1 (0.69) NPC1RAB9AHPGDSMN1; SMN2AR
SCHEMBL9732793 0.83 NPC1 (0.73) NPC1RAB9AHPGDSMN1; SMN2AR
SCHEMBL6575574 0.83 NPC1 (0.69) NPC1RAB9AHPGDSMN1; SMN2AR
SCHEMBL8795293 0.81 NPC1 (0.71) NPC1RAB9AHPGDSMN1; SMN2AR
SCHEMBL28680218 0.81 LMNA (0.62) SMN1; SMN2ARLMNAMAPK1ALDH1A1
SCHEMBL9389817 0.81 NPC1 (0.67) NPC1RAB9AHPGDSMN1; SMN2AR
SCHEMBL9732903 0.81 NPC1 (0.71) NPC1RAB9AHPGDSMN1; SMN2AR
SCHEMBL10461990 0.81 NPC1 (0.71) NPC1RAB9AHPGDSMN1; SMN2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129308-B2 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20090011154-A1 THERMAL TRANSFER IMAGE-RECEIVING SHEET AND SURFACE CONDITION IMPROVER FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed