Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.64 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.62 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222717 | 0.91 | TMIGD3 (0.63) | CDK1TMIGD3ADORA2AADORA1CCNB2 | |
| SCHEMBL9224998 | 0.88 | CDK1 (0.67) | CDK1TMIGD3ADORA2AADORA1CCNB2 | |
| SCHEMBL9222291 | 0.87 | TMIGD3 (0.58) | CDK1TMIGD3ADORA2AADORA1CCNB2 | |
| SCHEMBL17450225 | 0.84 | CDK1 (0.49) | CDK1TMIGD3ADORA2AADORA1CCNB2 | |
| SCHEMBL22571186 | 0.79 | TMIGD3 (0.81) | CDK1TMIGD3ADORA2AADORA1CCNB2 | |
| SCHEMBL4382069 | 0.78 | CDK1 (1.00) | CDK1TMIGD3ADORA2AADORA1CCNB2 | |
| SCHEMBL27967736 | 0.78 | RAB9A (0.70) | CDK1TMIGD3ADORA2AADORA1CCNB2 | |
| SCHEMBL27965570 | 0.78 | CDK1 (0.74) | CDK1TMIGD3ADORA2AADORA1CCNB2 | |
| SCHEMBL8378683 | 0.77 | CDK1 (0.69) | CDK1TMIGD3ADORA2AADORA1CCNB2 | |
| SCHEMBL27734468 | 0.77 | TMIGD3 (1.00) | CDK1TMIGD3ADORA2AADORA1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411929-A | Thermally-processable image recording materials including substituted purine compounds | POLAROID CORPORATION (US) | 1995-05-02 | — | — | US | claimed |
| US-5411929-A | Thermally-processable image recording materials including substituted purine compounds | POLAROID CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |