Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356694 | 0.89 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9353041 | 0.85 | ALOX5 (1.00) | ALOX5ADAM17 | |
| SCHEMBL9388482 | 0.85 | ALOX5 (0.80) | ALOX5ADAM17 | |
| SCHEMBL9352781 | 0.85 | ALOX5 (0.80) | ALOX5ADAM17 | |
| SCHEMBL9226727 | 0.84 | ALOX5 (1.00) | ALOX5ADAM17 | |
| SCHEMBL9388503 | 0.84 | ALOX5 (0.79) | ALOX5ADAM17 | |
| SCHEMBL9228533 | 0.84 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9356503 | 0.84 | ALOX5 (0.79) | ALOX5ADAM17 | |
| Ethylene SCHEMBL9356405 | 0.83 | ALOX5 (0.96) | ALOX5ADAM17 | |
| SCHEMBL9393716 | 0.82 | ALOX5 (0.76) | ALOX5ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403859-A | PHENYLENE-CYCLIC ETHER COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-04-04 | — | — | US | disclosed |
| EP-0375404-B1 | Heterocyclic derivatives | ICI PLC (GB) | 1994-02-09 | — | — | EP | disclosed |
| US-5234950-A | Antiallergens, antiinflammatory agents; cardiovascular disorders, antiarthritic | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-10 | — | — | US | disclosed |
| US-5098930-A | Inhibitors of lipoxygenase for treatment of diseases mediated with leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-24 | — | — | US | disclosed |
| EP-0375404-A2 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-27 | — | — | EP | disclosed |