SCHEMBL9223642

SCHEMBL9223642

C[C@@H](O)C(C(=O)OC(c1ccccc1)c1ccccc1)N1C(=O)C(N2C(=O)c3ccccc3C2=O)C1C=Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 11/20 0.52
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9223636 1.00 AVPR1A (0.52) AVPR1AMEN1KMT2APOLB
SCHEMBL9222227 0.88 AVPR1A (0.45) AVPR1AMEN1KMT2A
SCHEMBL9222223 0.88 AVPR1A (0.45) AVPR1AMEN1KMT2A
SCHEMBL9225933 0.85 AVPR1A (0.68) AVPR1AMEN1KMT2APOLB
SCHEMBL9225930 0.85 AVPR1A (0.68) AVPR1AMEN1KMT2APOLB
SCHEMBL9219422 0.82 AVPR1A (0.35) AVPR1AKMT2APOLB
SCHEMBL9219416 0.82 AVPR1A (0.35) AVPR1AKMT2APOLB
SCHEMBL10677562 0.81 AVPR1A (0.56) AVPR1AMEN1KMT2APOLB
SCHEMBL10680024 0.81 AVPR1A (0.56) AVPR1AMEN1KMT2APOLB
SCHEMBL10675501 0.81 AVPR1A (0.56) AVPR1AMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282895-B1 2-oxa-isocephem compounds, compositions containing same and processes for preparing same OTSUKA PHARMA CO LTD (JP) 1995-06-07 EP disclosed
US-5037976-A Antimicrobial Agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-08-06 US disclosed
US-4898859-A 2-Oxa-isocephem compounds and compositions containing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-02-06 US disclosed
EP-0282895-A2 2-oxa-isocephem compounds, compositions containing same and processes for preparing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-09-21 EP disclosed