Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219416 | 1.00 | AVPR1A (0.35) | AVPR1APOLBMAPTLMNATP53 | |
| SCHEMBL9219243 | 0.88 | ACHE (0.39) | MAPTKMT2A | |
| SCHEMBL9219236 | 0.88 | ACHE (0.39) | MAPTKMT2A | |
| SCHEMBL9225461 | 0.84 | AVPR1A (0.47) | AVPR1AHSD11B1CYP3A4CYP2C19 | |
| SCHEMBL9225470 | 0.84 | AVPR1A (0.47) | AVPR1AHSD11B1CYP3A4CYP2C19 | |
| SCHEMBL9223642 | 0.82 | AVPR1A (0.52) | AVPR1APOLBKMT2A | |
| SCHEMBL9223636 | 0.82 | AVPR1A (0.52) | AVPR1APOLBKMT2A | |
| SCHEMBL9224944 | 0.73 | ACHE (0.43) | AVPR1A | |
| SCHEMBL9222223 | 0.72 | AVPR1A (0.45) | AVPR1AMAPTKMT2A | |
| SCHEMBL9222227 | 0.72 | AVPR1A (0.45) | AVPR1AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282895-B1 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMA CO LTD (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5037976-A | Antimicrobial Agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| US-4898859-A | 2-Oxa-isocephem compounds and compositions containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0282895-A2 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |