Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.53 |
| ▸ | GRM8 | O00222 | 1/20 | 0.53 |
| ▸ | GRM6 | O15303 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225913 | 1.00 | NOD1 (0.57) | NOD1PTGS1GSTK1FOLH1GRM8 | |
| SCHEMBL6021265 | 1.00 | NOD1 (0.57) | NOD1PTGS1GSTK1FOLH1GRM8 | |
| SCHEMBL10423054 | 1.00 | NOD1 (0.57) | NOD1PTGS1GSTK1FOLH1GRM8 | |
| SCHEMBL10422367 | 1.00 | NOD1 (0.57) | NOD1PTGS1GSTK1FOLH1GRM8 | |
| SCHEMBL10421657 | 0.94 | PTGS1 (0.56) | NOD1PTGS1GSTK1FOLH1GRM8 | |
| SCHEMBL14496235 | 0.88 | NOD1 (0.50) | NOD1PTGS1GSTK1FOLH1GLO1 | |
| SCHEMBL30117079 | 0.88 | NOD1 (0.56) | NOD1PTGS1GSTK1FOLH1GRM8 | |
| SCHEMBL6853383 | 0.86 | FOLH1 (0.64) | NOD1PTGS1GSTK1FOLH1GRM8 | |
| SCHEMBL12210209 | 0.86 | FOLH1 (0.64) | NOD1PTGS1GSTK1FOLH1GRM8 | |
| SCHEMBL9225173 | 0.86 | FOLH1 (0.64) | NOD1PTGS1GSTK1FOLH1GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5444061-A | Antitumor agents | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-08-22 | — | — | US | claimed |
| US-4975418-A | Therapeutically active compositions of pseudo-peptide of glutamyl-aspartic acid | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIC (CNRS) (FR) | 1990-12-04 | — | — | US | claimed |
| US-4975418-A | Therapeutically active compositions of pseudo-peptide of glutamyl-aspartic acid | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIC (CNRS) (FR) | 1990-12-04 | — | — | US | disclosed |