SCHEMBL9224804

SCHEMBL9224804

CO[Si](CCC#N)(CCC#N)OC

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 2/20 0.33
LOX P28300 1/20 0.30
LOXL3 P58215 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2501144 0.87 TSHR (0.35) ALDH1A1TDP1TSHR
SCHEMBL1584800 0.84 TSHR (0.42) ALDH1A1TDP1TSHR
SCHEMBL9330179 0.83
SCHEMBL9228175 0.78 ALDH1A1 (0.37) ALDH1A1TDP1TSHRLOXLOXL3
SCHEMBL235898 0.78 ALDH1A1 (0.37) ALDH1A1TDP1TSHRLOXLOXL3
SCHEMBL9329179 0.76 ALDH1A1 (0.35) ALDH1A1TDP1TSHR
SCHEMBL601626 0.76 ALDH1A1 (0.35) ALDH1A1TDP1TSHR
SCHEMBL2501147 0.76
SCHEMBL2947294 0.75 TSHR (0.34) TSHR
SCHEMBL22472156 0.74 TSHR (0.33) ALDH1A1TDP1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0682034-A2 Process for organooxylation of cyanoalkylchlorosilanes DOW CORNING CORPORATION (US) 1995-11-15 EP disclosed
US-5374757-A Alcoholic esterification of silicon atom to form B-cyanoalkyl-organooxysilane; using falling-film or wiped-film type reactor DOW CORNING CORPORATION (US) 1994-12-20 US disclosed