SCHEMBL9224875

SCHEMBL9224875

CCCCCCCCCC(F)c1cc(O)ccc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.46
HTT P42858 1/20 0.44
KAT8 Q9H7Z6 2/20 0.43
KDM4E B2RXH2 1/20 0.43
RARB P10826 3/20 0.42
ALDH1A1 P00352 3/20 0.42
RARA P10276 1/20 0.42
RARG P13631 1/20 0.42
MAPT P10636 1/20 0.41
CYSLTR2 Q9NS75 1/20 0.41
CYSLTR1 Q9Y271 1/20 0.41
NAAA Q02083 1/20 0.41
PPARG P37231 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
TSHR P16473 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1487539 0.88 CA12 (0.44) PPARAHTTKDM4EALDH1A1CA12
SCHEMBL129098 0.86 PPARA (0.48) PPARAHTTKAT8KDM4ERARB
SCHEMBL5179731 0.86 PPARA (0.48) PPARAHTTKAT8KDM4ERARB
SCHEMBL9746372 0.84 PPARA (0.47) PPARAHTTKAT8KDM4ERARB
SCHEMBL9342860 0.84 PPARA (0.47) PPARAHTTKAT8KDM4ERARB
SCHEMBL9342859 0.84 PPARA (0.47) PPARAHTTKAT8KDM4ERARB
SCHEMBL6871353 0.84 PPARA (0.47) PPARAHTTKAT8KDM4ERARB
SCHEMBL5180293 0.83 PPARA (0.46) PPARAHTTKAT8KDM4ERARB
SCHEMBL29011410 0.83 TSHR (0.51) KDM4EALDH1A1TSHRLMNASMN1; SMN2
SCHEMBL9550240 0.83 PPARA (0.43) PPARAHTTKAT8KDM4ERARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0422996-B1 Liquid crystal compound SHOWA SHELL SEKIYU (JP) 1995-04-12 EP disclosed
US-5328641-A Naphthalene ester derivatives with trifluoromethyl groups SHOWA SHELL SEKIYU KABUSHIKI KAISHA 1994-07-12 US disclosed
US-5207947-A Trifluoroalkyl diaryl triesters; antiferroelectricity; electrooptics SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1993-05-04 US disclosed
EP-0422996-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-04-17 EP disclosed