Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225068 | 0.88 | ALOX5 (0.59) | ALOX5ADAM17 | |
| SCHEMBL9223138 | 0.88 | ALOX5 (0.66) | ALOX5ADAM17 | |
| SCHEMBL9211017 | 0.86 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL9352673 | 0.85 | ALOX5 (0.63) | ALOX5ADAM17 | |
| SCHEMBL9352666 | 0.85 | ALOX5 (0.63) | ALOX5ADAM17 | |
| SCHEMBL9352661 | 0.85 | ALOX5 (0.63) | ALOX5ADAM17 | |
| SCHEMBL9389854 | 0.85 | ALOX5 (0.63) | ALOX5ADAM17 | |
| SCHEMBL9353131 | 0.84 | ALOX5 (0.65) | ALOX5ADAM17 | |
| SCHEMBL9224997 | 0.82 | ALOX5 (0.64) | ALOX5ADAM17 | |
| SCHEMBL9279813 | 0.82 | ALOX5 (0.41) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403859-A | PHENYLENE-CYCLIC ETHER COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-04-04 | — | — | US | disclosed |
| US-5234950-A | Antiallergens, antiinflammatory agents; cardiovascular disorders, antiarthritic | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-10 | — | — | US | disclosed |
| US-5098930-A | Inhibitors of lipoxygenase for treatment of diseases mediated with leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-24 | — | — | US | disclosed |