Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 13/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 13/20 | 0.48 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216791 | 0.96 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9221749 | 0.94 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9222038 | 0.90 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9219102 | 0.90 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9225337 | 0.89 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL7679644 | 0.88 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9221839 | 0.88 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9218919 | 0.88 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9225799 | 0.87 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9225094 | 0.87 | AGTR1 (0.48) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451592-A | Angiotensin antagonist | C.D. SEARLE & CO. (US) | 1995-09-19 | — | — | US | disclosed |