Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377786 | 0.89 | ITGB3 (0.57) | ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL8377790 | 0.89 | ITGB3 (0.57) | ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL8379235 | 0.84 | ITGB3 (0.73) | ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL8379238 | 0.84 | ITGB3 (0.73) | ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL9223584 | 0.83 | ITGB3 (0.80) | ITGB3ITGA2B | |
| SCHEMBL7331297 | 0.83 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Iodide SCHEMBL9225689 | 0.82 | ITGB3 (0.98) | ITGB3ITGA2B | |
| SCHEMBL7296779 | 0.81 | ITGB3 (0.54) | ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL8647567 | 0.80 | MEN1 (0.51) | ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL8643669 | 0.80 | ITGB3 (0.53) | ITGB3ITGA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |