Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CSF1R | P07333 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MARK3 | P27448 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502760 | 0.81 | CSF1R (0.60) | L3MBTL1CSF1REGFRLRRK2HTT | |
| Dimethyladenine SCHEMBL152593 | 0.74 | LRRK2 (0.52) | CSF1REGFRCYP2D6JAK3LRRK2 | |
| SCHEMBL8495356 | 0.73 | CSF1R (0.36) | L3MBTL1CSF1REGFRJAK2LRRK2 | |
| SCHEMBL10645656 | 0.73 | CSF1R (0.36) | L3MBTL1CSF1REGFRLRRK2HTT | |
| Dimethyladenine SCHEMBL11157543 | 0.73 | LRRK2 (0.50) | CSF1REGFRCYP2D6JAK3LRRK2 | |
| SCHEMBL6517684 | 0.73 | LRRK2 (0.42) | CSF1REGFRJAK2JAK3LRRK2 | |
| Dimethyladenine SCHEMBL28476806 | 0.73 | LRRK2 (0.50) | CSF1REGFRCYP2D6JAK3LRRK2 | |
| SCHEMBL29100435 | 0.72 | LRRK2 (0.41) | CSF1REGFRJAK2JAK3LRRK2 | |
| SCHEMBL9219718 | 0.71 | CSF1R (0.63) | CSF1REGFRHTTKDM4ELMNA | |
| SCHEMBL10649356 | 0.70 | CSF1R (0.39) | CSF1REGFRJAK3LRRK2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411929-A | Thermally-processable image recording materials including substituted purine compounds | POLAROID CORPORATION (US) | 1995-05-02 | — | — | US | claimed |
| US-5411929-A | Thermally-processable image recording materials including substituted purine compounds | POLAROID CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |