Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MARK3 | P27448 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502760 | 0.77 | CSF1R (0.60) | CSF1REGFRHTTLRRK2ALDH1A1 | |
| SCHEMBL10649356 | 0.75 | CSF1R (0.39) | CSF1REGFRLRRK2CHEK1AURKA | |
| Dimethyladenine SCHEMBL152593 | 0.73 | LRRK2 (0.52) | CSF1REGFRHTTLRRK2CHEK1 | |
| SCHEMBL9225650 | 0.73 | L3MBTL1 (0.58) | CSF1REGFRSMN1; SMN2LMNAHTT | |
| SCHEMBL8495356 | 0.72 | CSF1R (0.36) | CSF1REGFRSMN1; SMN2HPGDTSHR | |
| Dimethyladenine SCHEMBL28476806 | 0.72 | LRRK2 (0.50) | CSF1REGFRHTTLRRK2CHEK1 | |
| Dimethyladenine SCHEMBL11157543 | 0.72 | LRRK2 (0.50) | CSF1REGFRHTTLRRK2CHEK1 | |
| SCHEMBL6517684 | 0.72 | LRRK2 (0.42) | CSF1REGFRSMN1; SMN2HTTLRRK2 | |
| SCHEMBL13987915 | 0.71 | CSF1R (0.41) | CSF1REGFR | |
| SCHEMBL29100435 | 0.71 | LRRK2 (0.41) | CSF1REGFRSMN1; SMN2HTTLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4718936-A | PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1988-01-12 | — | — | US | disclosed |
| EP-0154937-A2 | 6-(3-Thienylmethylamino)-purin, process for its preparation and its use | BASF Aktiengesellschaft (DE) | 1985-09-18 | — | — | EP | disclosed |