Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.53 |
| ▸ | MELK | Q14680 | 1/20 | 0.53 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.53 |
| ▸ | TYMS | P04818 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349435 | 0.84 | JAK2 (0.54) | JAK2RPS6KA3MELKSTK24TYMS | |
| SCHEMBL65699 | 0.84 | JAK2 (0.54) | JAK2RPS6KA3MELKSTK24TYMS | |
| SCHEMBL28276823 | 0.82 | JAK2 (0.52) | JAK2RPS6KA3MELKSTK24TYMS | |
| Fluoride SCHEMBL11274176 | 0.82 | JAK2 (0.52) | JAK2RPS6KA3MELKSTK24TYMS | |
| SCHEMBL28313238 | 0.82 | JAK2 (0.52) | JAK2RPS6KA3MELKSTK24TYMS | |
| Hydrochloric Acid SCHEMBL11277860 | 0.82 | JAK2 (0.52) | JAK2RPS6KA3MELKSTK24TYMS | |
| Hydrochloric Acid SCHEMBL11698588 | 0.82 | JAK2 (0.52) | JAK2RPS6KA3MELKSTK24TYMS | |
| SCHEMBL9627127 | 0.82 | JAK2 (0.52) | JAK2RPS6KA3MELKSTK24TYMS | |
| Ammonia Solution, Strong SCHEMBL2638226 | 0.82 | JAK2 (0.52) | JAK2RPS6KA3MELKSTK24TYMS | |
| SCHEMBL28296931 | 0.82 | JAK2 (0.52) | JAK2RPS6KA3MELKSTK24TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457170-A | Coating interior wall of vessel used for addition polymerization | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| US-5424003-A | Preventive coatings for equipment and reactors used for addition polymerization of unsaturated compounds; antideposit agents; amino resins | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |