Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | MPO | P05164 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CTSC | P53634 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL9225863 | 1.00 | KDM4E (0.65) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL27443674 | 0.98 | KDM4E (0.68) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL8366911 | 0.97 | KDM4E (0.70) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL8366914 | 0.97 | KDM4E (0.70) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL7356311 | 0.95 | KDM4E (0.73) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL7356323 | 0.95 | KDM4E (0.73) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL22091568 | 0.94 | KDM4E (0.74) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL7154073 | 0.94 | KDM4E (0.74) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL7859113 | 0.94 | KDM4E (0.74) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL28120361 | 0.93 | KDM4E (0.76) | KDM4EMAPTKMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665897-A4 | COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS. | UNIV COLUMBIA (US) | 1995-09-27 | — | — | EP | disclosed |
| EP-0665897-A1 | COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994008051-A1 | COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1994-04-14 | — | — | WO | disclosed |