Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL613941 | 0.96 | — | — | |
| Ether SCHEMBL9339223 | 0.96 | ALDH1A1 (0.46) | ALDH1A1TSHRFFAR3LMNAHSD17B10 | |
| Ether SCHEMBL28299459 | 0.93 | ALDH1A1 (0.43) | ALDH1A1TSHRFFAR3LMNAHSD17B10 | |
| Ether SCHEMBL29058438 | 0.93 | ALDH1A1 (0.43) | ALDH1A1TSHRFFAR3LMNAHSD17B10 | |
| Ether SCHEMBL17766472 | 0.90 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3LMNAHSD17B10 | |
| Ether SCHEMBL2910547 | 0.90 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR3LMNAHSD17B10 | |
| Ether SCHEMBL7854226 | 0.90 | ALDH1A1 (0.42) | ALDH1A1TSHRFFAR3LMNAHSD17B10 | |
| Ether SCHEMBL7115101 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRFFAR3LMNAHSD17B10 | |
| Ether SCHEMBL20338904 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRFFAR3LMNAHSD17B10 | |
| Oxalic Acid SCHEMBL5756637 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TSHRFFAR3LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5445701-A | Apparatus of manufacturing a sheet-prepreg reinforced with fibers | RESEARCH ASSOCIATION FOR NEW TECHNOLOGY DEVELOPMENT OF HIGH PERFORMANCE POLYMER (JP) | 1995-08-29 | — | — | US | disclosed |