Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482204 | 0.80 | KDM4E (0.73) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL8107 | 0.78 | KDM4E (0.71) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL1216700 | 0.78 | CYP2D6 (0.40) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL27043265 | 0.77 | KDM4E (0.54) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL10596212 | 0.77 | TSHR (0.75) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL14441639 | 0.74 | — | — | |
| SCHEMBL12891506 | 0.74 | KDM4E (0.64) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL860791 | 0.73 | KDM4E (0.94) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL1900471 | 0.73 | KDM4E (0.82) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL31565700 | 0.72 | KDM4E (0.48) | KDM4EMAPK1HIF1ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378430-B1 | Novel organosilicon compound and process for producing organosilicon compound | AGENCY IND SCIENCE TECHN (JP) | 1995-02-01 | — | — | EP | disclosed |
| US-5151538-A | ORGANOSILICON COMPOUND AND PROCESS FOR PRODUCING ORGANOSILICON COMPOUND | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1992-09-29 | — | — | US | disclosed |