SCHEMBL9225980

SCHEMBL9225980

CCCN(CCC)C(Cc1ccccc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
ALPI P09923 1/20 0.46
PKM P14618 1/20 0.46
PTGS1 P23219 1/20 0.46
XIAP P98170 1/20 0.46
SLC7A5 Q01650 1/20 0.46
MAPT P10636 2/20 0.44
ALDH1A1 P00352 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ADAMTS5 Q9UNA0 1/20 0.44
CPA1 P15085 3/20 0.43
CPA3 P15088 2/20 0.43
FOLH1 Q04609 1/20 0.43
CPB1 P15086 1/20 0.43
CPB2 Q96IY4 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9225983 1.00 CYP1A2 (0.48) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL15044785 0.87 CSNK1E (0.46) CYP1A2MEN1KMT2ANPC1RAB9A
SCHEMBL16525596 0.87 CSNK1E (0.46) CYP1A2MEN1KMT2ANPC1RAB9A
SCHEMBL28357249 0.87 CSNK1E (0.46) CYP1A2MEN1KMT2ANPC1RAB9A
SCHEMBL28357247 0.87 CSNK1E (0.46) CYP1A2MEN1KMT2ANPC1RAB9A
SCHEMBL1063981 0.86 CYP1A2 (0.52) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL1063983 0.86 CYP1A2 (0.52) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL17773059 0.85 NR4A2 (0.49) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL5572812 0.85 CYP1A2 (0.47) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL8950931 0.84 CYP1A2 (0.50) CYP1A2ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1065874-C Novel peptides, the preparation and use thereof BASF AG (DE) 2001-05-16 CN disclosed
EP-0642530-A1 DERIVATIVES OF DOLASTATIN BASF Aktiengesellschaft (DE) 1995-03-15 EP disclosed
CN-1085563-A New peptide and preparation thereof and application BASF AG (DE) 1994-04-20 CN disclosed