Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CPA1 | P15085 | 3/20 | 0.46 |
| ▸ | CPA3 | P15088 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063981 | 1.00 | CYP1A2 (0.52) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL28810476 | 0.90 | ALDH1A1 (0.52) | MAPTALDH1A1CPA1ADAMTS5SRR | |
| SCHEMBL28810475 | 0.90 | ALDH1A1 (0.52) | MAPTALDH1A1CPA1ADAMTS5SRR | |
| SCHEMBL16450888 | 0.87 | ALPI (0.47) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL30736141 | 0.86 | SLC7A5 (0.51) | SLC7A5CPA1FOLH1POLB | |
| SCHEMBL9225983 | 0.86 | CYP1A2 (0.48) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL9225980 | 0.86 | CYP1A2 (0.48) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL4237993 | 0.85 | KCNH2 (0.47) | CYP1A2KCNH2NPC1RAB9ALMNA | |
| SCHEMBL16449790 | 0.84 | PGR (0.47) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL16572639 | 0.84 | CYP1A2 (0.50) | CYP1A2ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908873-A | Amino acid derivatization reagent pair based on unstable isotope labeling and preparation method and application thereof | 郑州大学 | 2024-11-08 | — | — | CN | claimed |
| CN-118908873-B | Amino acid derivatization reagent pair based on unstable isotope labeling and preparation method and application thereof | 郑州大学 | 2025-10-03 | — | — | CN | disclosed |
| CN-118908873-A | Amino acid derivatization reagent pair based on unstable isotope labeling and preparation method and application thereof | 郑州大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-118908873-A | Amino acid derivatization reagent pair based on unstable isotope labeling and preparation method and application thereof | 郑州大学 | 2024-11-08 | — | — | CN | disclosed |
| US-20240036055-A1 | Multiplexed DiLeu-Biotin-Azide (DBA) Tag Enabled Isobaric Tandem Orthogonal Proteolysis Activity-Based Protein Profiling (isoBOP-ABPP) Platform For High-Throughput Quantitative Pan-PTM Analysis | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2024-02-01 | — | — | US | disclosed |
| WO-2018178397-A1 | N-ALKYLATED AMINO ACIDS AND OLIGOPEPTIDES, USES THEREOF AND METHODS FOR PROVIDING THEM. | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2018-10-04 | — | — | WO | disclosed |
| EP-2861610-A1 | N-SUBSTITUTED SECOND GENERATION DERIVATIVES OF ANTIFUNGAL ANTIBIOTIC AMPHOTERICIN B AND METHODS OF THEIR PREPARATION AND APPLICATION | Blirt S.A. (PL) | 2015-04-22 | — | — | EP | disclosed |
| CN-104520309-A | N-substituted second generation derivatives of antifungal antibiotic amphotericin B and methods of their preparation and application | BLIRT SA | 2015-04-15 | — | — | CN | disclosed |
| US-20150079179-A1 | SUSTAINED RELEASE FORMULATIONS OF PEPTIDOMIMETIC DRUGS AND USES THEREOF | JERINI OPHTHALMIC INC (US) | 2015-03-19 | — | — | US | disclosed |
| WO-2013186384-A1 | N-SUBSTITUTED SECOND GENERATION DERIVATIVES OF ANTIFUNGAL ANTIBIOTIC AMPHOTERICIN B AND METHODS OF THEIR PREPARATION AND APPLICATION | BLIRT S.A. (PL) | 2013-12-19 | — | — | WO | disclosed |
| US-20120244192-A1 | SUSTAINED RELEASE FORMULATIONS OF PEPTIDOMIMETIC DRUGS AND USES THEREOF | JERINI OPHTHALMIC INC. | 2012-09-27 | — | — | US | disclosed |
| US-20110003756-A1 | C5a Receptor Antagonists | JERINI AG (DE) | 2011-01-06 | — | — | US | disclosed |
| US-7727960-B2 | C5a receptor antagonists | JERINI AG (DE) | 2010-06-01 | — | — | US | disclosed |
| US-20080161232-A1 | C5a is a cleavage product of the complement cascade, the CS convertase; antiinflammatory agents; autoimmune diseases; cyclic peptide compounds | JERINI AG (DE) | 2008-07-03 | — | — | US | disclosed |
| CN-101107264-A | C5a receptor antagonists | JERINI AG (DE) | 2008-01-16 | — | — | CN | disclosed |
| US-20060183883-A1 | C5a Receptor antagonists | JERINI AG (DE) | 2006-08-17 | — | — | US | disclosed |
| EP-0642530-A1 | DERIVATIVES OF DOLASTATIN | BASF Aktiengesellschaft (DE) | 1995-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183883-A1 | C5a Receptor antagonists | C5AR1, C3AR1, C5AR2 | CYP1A2 1583/4885ALPI 4882/4885PKM 4260/4885 |
| US-20110003756-A1 | C5a Receptor Antagonists | C5AR1, C3AR1, C5AR2 | CYP1A2 1313/4885ALPI 4868/4885PKM 4353/4885 |
| US-20080161232-A1 | C5a is a cleavage product of the complement cascade, the CS convertase; antiinflammatory agents; autoimmune diseases; cyclic peptide compounds | C3AR1, C5, C5AR1 | CYP1A2 2945/4885ALPI 4766/4885PKM 4445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.