Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 17/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9224855 | 0.99 | RXFP1 (0.52) | RXFP1GAAPTGS1ALDH1A1 | |
| SCHEMBL9220315 | 0.85 | RXFP1 (0.57) | RXFP1GAAPTGS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9229016 | 0.84 | RXFP1 (0.56) | RXFP1GAAPTGS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9227330 | 0.83 | NR1H4 (0.47) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9228583 | 0.82 | RXFP1 (0.58) | RXFP1GAAPTGS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9220369 | 0.82 | NAMPT (0.55) | RXFP1GAAPTGS1ALDH1A1 | |
| SCHEMBL9221688 | 0.78 | NR1H4 (0.49) | RXFP1 | |
| SCHEMBL9226877 | 0.76 | NAMPT (0.45) | PTGS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9224852 | 0.76 | NAMPT (0.44) | PTGS1ALDH1A1 | |
| SCHEMBL9229693 | 0.75 | RXFP1 (0.50) | RXFP1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | claimed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | claimed |
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |