Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | F13A1 | P00488 | 4/20 | 0.52 |
| ▸ | TGM1 | P22735 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29571128 | 0.81 | KMT2A (0.68) | ALDH1A1KMT2AF13A1TGM1MEN1 | |
| SCHEMBL31284709 | 0.81 | KMT2A (0.68) | ALDH1A1KMT2AF13A1TGM1MEN1 | |
| SCHEMBL27006685 | 0.81 | KMT2A (0.68) | ALDH1A1KMT2AF13A1TGM1MEN1 | |
| SCHEMBL9229237 | 0.81 | IKBKB (0.43) | ALDH1A1KMT2ACYP19A1LMNA | |
| SCHEMBL9226499 | 0.81 | POLB (0.64) | ALDH1A1KMT2AF13A1TGM1CYP19A1 | |
| SCHEMBL3540913 | 0.79 | KMT2A (0.66) | ALDH1A1KMT2AF13A1TGM1MEN1 | |
| SCHEMBL8578058 | 0.79 | KMT2A (0.61) | ALDH1A1KMT2AMEN1CYP19A1NPY5R | |
| SCHEMBL31720671 | 0.78 | KAT2B (0.57) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL30649118 | 0.78 | KMT2A (0.71) | ALDH1A1KMT2AMEN1CYP19A1NPY5R | |
| SCHEMBL4389696 | 0.78 | KMT2A (0.71) | ALDH1A1KMT2AMEN1CYP19A1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |