Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227906 | 0.81 | ALDH1A1 (0.56) | CYP19A1KMT2AALDH1A1LMNA | |
| SCHEMBL9227357 | 0.80 | IKBKB (0.66) | IKBKBQPCTCYP19A1KMT2AALDH1A1 | |
| SCHEMBL18989501 | 0.76 | CA9 (0.61) | CA9KMT2ANSD2RECQLCA12 | |
| SCHEMBL4068334 | 0.75 | RECQL (0.66) | CA9KMT2ANSD2RECQLCA12 | |
| SCHEMBL27855398 | 0.74 | RECQL (0.68) | CA9KMT2ANSD2RECQLCA12 | |
| SCHEMBL14572311 | 0.74 | RECQL (0.68) | CA9KMT2ANSD2RECQLCA12 | |
| SCHEMBL448186 | 0.73 | CA9 (0.53) | CA9NSD2FLT3CA12ALDH1A1 | |
| SCHEMBL375546 | 0.73 | CA9 (0.59) | CA9NSD2RECQLCA12CYP2C9 | |
| SCHEMBL4036900 | 0.72 | ALDH1A1 (0.52) | KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL10372501 | 0.72 | ALDH1A1 (0.55) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |