SCHEMBL9228015

SCHEMBL9228015

CC(C)(C)c1ccc(C2(C)CC(C)(CC(C)(C)c3ccccc3)c3ccccc32)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FSHR P23945 1/20 0.36
KIF11 P52732 1/20 0.35
TAAR1 Q96RJ0 1/20 0.33
ICMT O60725 1/20 0.33
TP53 P04637 4/20 0.32
MAPT P10636 2/20 0.32
PLIN1 O60240 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PLIN5 Q00G26 1/20 0.32
ABHD5 Q8WTS1 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.32
ADRB2 P07550 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ATM Q13315 1/20 0.32
RAB9A P51151 2/20 0.31
LMNA P02545 1/20 0.31
MDM2 Q00987 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9226784 0.97 FSHR (0.35) FSHRKIF11ICMTTP53MAPT
SCHEMBL9230073 0.96 FSHR (0.39) FSHRKIF11TAAR1ICMTTP53
SCHEMBL7930754 0.92 TP53 (0.37) FSHRTAAR1TP53MAPTPLIN1
SCHEMBL9232043 0.84 MEN1 (0.38) FSHRKIF11TP53MAPTALDH1A1
SCHEMBL9228008 0.82 TAAR1 (0.34) TAAR1
SCHEMBL9230922 0.82 MEN1 (0.36) FSHRKIF11TP53MAPTMEN1
SCHEMBL9232359 0.81 MEN1 (0.41) FSHRKIF11TP53MAPTMEN1
SCHEMBL10001138 0.80 TP53 (0.34) FSHRTP53MAPTMEN1ADRB2
SCHEMBL9230065 0.80 TP53 (0.35) FSHRTP53MAPTPLIN1ALDH1A1
SCHEMBL9230020 0.76 ATM (0.37) FSHRKIF11ICMTTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397383-A Stryrene-indene dimers, trimers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-14 US disclosed
EP-0611627-A2 Organic vehicle for electronic composition E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-08-24 EP disclosed