Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | FSHR | P23945 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232043 | 0.96 | MEN1 (0.38) | MEN1ADRB2KMT2ANPSR1EPHX2 | |
| SCHEMBL9232359 | 0.96 | MEN1 (0.41) | MEN1ADRB2KMT2ANPSR1EPHX2 | |
| SCHEMBL10001138 | 0.88 | TP53 (0.34) | MEN1ADRB2KMT2ANPSR1TP53 | |
| SCHEMBL9226784 | 0.84 | FSHR (0.35) | MEN1ADRB2KMT2ANPSR1TP53 | |
| SCHEMBL9228015 | 0.82 | FSHR (0.36) | MEN1ADRB2KMT2ANPSR1TP53 | |
| SCHEMBL7930754 | 0.82 | TP53 (0.37) | MEN1ADRB2KMT2ANPSR1TP53 | |
| SCHEMBL9230073 | 0.81 | FSHR (0.39) | MEN1ADRB2KMT2ANPSR1TP53 | |
| SCHEMBL9232039 | 0.79 | PDK2 (0.33) | MEN1ADRB2KMT2ANPSR1TP53 | |
| SCHEMBL9232353 | 0.78 | NPSR1 (0.41) | MEN1ADRB2KMT2ANPSR1TP53 | |
| SCHEMBL9812184 | 0.78 | RXRA (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397383-A | Stryrene-indene dimers, trimers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| US-5344592-A | Paste with inorganic particles | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0611627-A2 | Organic vehicle for electronic composition | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |